Searchable abstracts of presentations at key conferences in endocrinology

ea0081p512 | Late-Breaking | ECE2022

Changes in acromegaly presentation and treatment over a three-decade period

Aagaard Charlotte , S Christophersen Amanda , Finnerup Susanne , Rosendal Christian , Vestergaard Peter , Karmisholt Jesper , H Nielsen Eigil , Dal Jakob

Objective: To study time-dependent changes in the prevalence and patient characteristics of acromegaly, as well as to access the impact of changes in treatment on disease control.Methods: A total of 107 patients with acromegaly were identified by healthcare registries and subsequently validated by patient chart review over a three-decade period (1992-2021).Results: The prevalence of acromegaly significantly increased throughout the...

ea0090p405 | Pituitary and Neuroendocrinology | ECE2023

The TRH test is a valuable diagnostic test in central hypothyroidism with low T4

Norma Smith* Liv , Ellegaard Christensen* Sara , Rosendal Christian , Angela Gulisano Helga , Ettrup Kare , H Nielsen Eigil , Karmisholt Jesper , Dal Jakob

Objective: To evaluate the value of the thyrotropin-releasing hormone (TRH) test in the diagnosis of central hypothyroidism (CH) in patients with pituitary disease.Methods: Systematic evaluation of 368 TRH tests including measurements of TBG corrected thyroxine (T4corr), baseline TSH (TSH0) and fold and absolute TSH increase (TSHfold, TSHabsolute) in patients with pituitary disease.Result...